Your Doctor in Tricity guide to stress free healthcare
October 28, 2025Unified Commerce For B2B That Actually Works
October 28, 2025
The healthcare industry is undergoing a massive digital transformation. Hospitals, clinics, and startups across the United States are investing in advanced healthcare software development to improve patient outcomes, automate workflows, and ensure compliance with strict regulations like HIPAA and FDA standards. From AI-powered diagnostics to EHR integrations and telemedicine platforms, the demand for robust, secure, and scalable healthtech solutions is at an all-time high.
Choosing the right healthcare software development company can determine whether your project becomes a breakthrough success or gets stuck in compliance and scalability issues. Experienced partners bring not just technical skills but also deep domain knowledge — understanding the nuances of data privacy, interoperability, and patient-centric design.
In this article, we highlight the Top 10 Healthcare Software Development Companies in the USA that are setting the standard for innovation, quality, and reliability in 2025.
1. ScienceSoft
Location: Texas, USA
Expertise: EHR development, medical imaging, healthcare analytics
ScienceSoft has been a trusted name in software engineering for over three decades. Their healthcare division focuses on developing HIPAA-compliant medical software for hospitals, diagnostic centers, and research institutions. From EHR and HIE systems to telehealth and patient portals, ScienceSoft’s expertise lies in delivering secure, interoperable platforms that meet both clinical and business goals.
2. Onix Systems – Custom Healthcare Software Development & Rescue Experts
Location: USA & Ukraine
Expertise: Healthcare software rescue, custom healthtech solutions, AI-powered healthcare systems
Onix Systems is a custom healthcare software development company known for saving and scaling complex medical projects. Whether you’re dealing with a broken EMR, a non-compliant MVP, or a stalled telehealth platform, Onix provides end-to-end healthcare software development services to stabilize, rebuild, and modernize your product.
Their engineers specialize in HIPAA-compliant software, EHR and HIE integrations, AI-powered decision support, and healthcare CRM solutions. With a focus on compliance, transparency, and innovation, Onix helps healthcare organizations improve performance, reduce risk, and accelerate digital transformation.
What makes Onix unique is their rescue-first approach — stepping in to fix what others couldn’t. From rapid audits and legacy modernization to full-scale redevelopment, the team ensures every product is secure, scalable, and ready to perform in real-world healthcare environments.
3. Kanda Software
Location: Massachusetts, USA
Expertise: Cloud-based healthcare platforms, EHR, data analytics
Kanda Software builds custom healthcare and life sciences applications focused on interoperability and patient data management. Their cloud-first architecture and agile delivery models make them a reliable partner for startups and enterprise providers seeking scalable, secure, and compliant digital solutions.
4. Chetu Inc.
Location: Florida, USA
Expertise: Healthcare app development, custom APIs, medical billing
Chetu provides custom software solutions for healthcare organizations of all sizes. Their teams develop EHR, telehealth, and medical billing platforms tailored to each client’s operational needs. With over 2,000 developers worldwide, Chetu delivers large-scale healthtech systems while ensuring strong compliance with US healthcare standards.
5. Invonto
Location: New Jersey, USA
Expertise: Healthcare automation, mobile app development, workflow optimization
Invonto partners with hospitals and medical device companies to build healthcare mobile apps and workflow automation platforms. Their focus on user experience and compliance ensures that every product not only meets functional goals but also improves patient and clinician satisfaction.
6. Itransition
Location: Colorado, USA
Expertise: EHR development, AI and machine learning, data interoperability
Itransition is recognized for its extensive work in medical data exchange and interoperability. The company builds FHIR-compliant EHR and analytics solutions that help healthcare organizations make data-driven decisions while maintaining full compliance with HIPAA and HITECH standards.
7. Belitsoft
Location: Florida, USA
Expertise: Healthcare web apps, CRM, EMR software
Belitsoft develops custom healthcare CRM and EMR platforms designed to streamline patient management and improve provider collaboration. Their team brings strong expertise in building secure, cloud-based health systems that integrate seamlessly with third-party tools and IoT devices.
8. Andersen Inc.
Location: New York, USA
Expertise: Telemedicine platforms, AI-driven diagnostics, IoT health
Andersen delivers end-to-end healthcare software development services with a focus on AI, IoT, and predictive analytics. They help medical organizations adopt new technologies such as AI-powered symptom checkers and wearable integrations to improve patient outcomes.
9. Glorium Technologies
Location: New Jersey, USA
Expertise: Healthcare SaaS, HIPAA compliance, startup acceleration
Glorium specializes in building digital products for healthcare startups and mid-size providers. Their combination of UX/UI expertise, SaaS delivery, and strict compliance practices makes them a go-to partner for rapid product launches and growth.
10. Oxagile
Location: New York, USA
Expertise: Video-based telehealth, real-time data processing, healthtech consulting
Oxagile delivers complex telemedicine and remote patient monitoring solutions for US healthcare providers. Their focus on real-time communication and secure data transmission has made them a reliable vendor for large-scale medical networks.
Final Thoughts
Healthcare software development is one of the most challenging and rewarding areas in tech — requiring precision, compliance, and innovation in equal measure. The companies featured here have proven their ability to build scalable, secure, and user-centered solutions that drive real impact in hospitals, clinics, and research environments across the USA.
If you’re looking for a trusted partner that can handle the complexities of custom healthcare software development, consider working with Onix Systems. With a deep understanding of compliance frameworks like HIPAA and ISO 13485, advanced AI-driven solutions, and a proven track record of project recovery, Onix is the partner that helps healthcare innovators move from stalled to scalable — safely and effectively.
When patient outcomes depend on your technology, there’s no room for failure. Choose a healthcare software development partner that combines technical mastery, transparency, and long-term commitment — and build solutions that truly make a difference.
